UseGalaxy.eu Use Case: Antibody responses following vaccination

1 · useGalaxy.eu · Aug. 27, 2021, 1:06 p.m.
Carolyn Nielsen works on clinical immunology at the University of Oxford (UK). My project focuses on understanding the cellular drivers of antibody responses following vaccination, in particular in the impact of different dosing regimens. As part of this work, I have run a single cell RNA sequencing experiment (SmartSeq, Nextera, HiSeq4000) with sorted vaccine-specific B cells from two groups receiving malaria vaccines on either a ‘standard’ or ‘delayed’ dosing regimen. I am now analysing this ...