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A tutorial on using knitr in Eclipse by courtesy of Jenny Hutchison is available for download. It is probably too long for an experienced Eclipse user, and as a person who does not use Eclipse, I believe one screenshot can explain the setup: You do not have to follow this. For example, you can run knit() first to get the tex document, and let Eclipse compile tex to PDF; in the above configuration, the two steps were combined into one knit2pdf(). See the post in the blog Dang, another error for ...