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Posted by Marco Cuturi and Jean-Philippe Vert, Research Scientists, Google Research, Brain Team How does one find a needle in a haystack? At the turn of World War II, that question took on a very concrete form when doctors wondered how to efficiently detect diseases among those who had been drafted into the war effort. Inspired by this challenge, Robert Dorfman, a young statistician at that time (later to become Harvard professor of economics), proposed in a seminal paper a 2-stage approach to d...